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Circulating AIM as an Indicator of Liver Damage and Hepatocellular Carcinoma in Humans

Figure 3

The AIM level increases with progression of liver inflammation and fibrosis.

(A) Correlation in AIM and IgM levels in men (blue) and women (yellow), with or without HCC. (B) AIM levels in HCC patients with different inflammatory levels according to the Inuyama classification. (C) AIM levels in HCC patients with different fibrotic scores according to the Inuyama classification. (D) AIM levels in HCC patients with different grades of cirrhosis or ascites. In C-E, AIM levels are presented as means±SEM (µg/ml).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0109123.g003