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DNA Methylation Analysis in the Intestinal Epithelium—Effect of Cell Separation on Gene Expression and Methylation Profile

Figure 3

Analysis of cytosine methylation of promoter regions of selected genes.

A) CpG methylation of promoter regions of selected genes analysed by MeDIP. B) CpG methylation of promoter regions of selected genes analysed by pyrosequencing. Data is expressed as box and whisker plots. The length of the boxes represents the interquartile range and the whiskers the 3rd and 97th percentile of the data. Significance testing was performed using paired Students T-test and values for p<0.05 were considered to be statistically significant.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0055636.g003