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A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis

Figure 3

ELISPOT splenocyte responses.

These include responses to peptide pools, selected peptide (F9.1), and recombinant vaccine antigens (AhpC, Mpa) in Control (Grp 1) mice (C) and Vaccine (Grp 2) mice (V), 4 weeks after immunisation A) using pSG2-prime/MVA-boost (Experiment 1A) or B) Ad5-prime/MVA-boost (Experiment 1B). Significant responses are indicated.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0001229.g003