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Adverse prognosis of glioblastoma contacting the subventricular zone: Biological correlates

Fig 2

SVZ involvement associates with glioblastoma patient survival.

A. Pre-operative T1-weighted MRI scan with gadolinium of patient (M, 1928) with glioblastoma contacting the SVZ. B. Pre-operative T1-weighted MRI scan with gadolinium of patient (F, 1925) with glioblastoma not contacting the SVZ. C. Association of tumor contact with the SVZ on glioblastoma patient survival. Kaplan-Meier plot of glioblastoma patients with a tumor contacting the SVZ (grey) and patients with a tumor that does not contact the SVZ (black). Patients with survival over 1000 days from surgery were censored. Survival was significantly different between the two groups (log-rank test, P < 0.00005).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0222717.g002