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Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers

Fig 2

Candidate amino acid sites under positive selection in RHAMM and BRCA1.

(A) Plot showing the position of potentially selected sites (p (w > 1)) in the amino acid sequence of RHAMM. The relative position of known protein domains is shown. (B) Plot showing the position of potentially selected sites (p (w > 1)) in the amino acid sequence of BRCA1. The relative position of known protein domains is shown.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0120020.g002