Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer
Figure 2
Regional interaction association plot for interacting region 5q21 with known CRC locus rs10795668.
The left y-axis shows the -log10 of the meta-analysis interaction p value. The right y-axis shows the recombination rate. Each dot on the plot represents the result for one SNP. The diamond dot represents SNP rs367615 and the round dots represent other SNPs. Difference colors of SNPs indicate different LD strength between the corresponding SNP and rs367615, measured by r2. The bottom of the figure shows the genes in the plotted region.