Plasma Free Amino Acid Profiling of Five Types of Cancer Patients and Its Application for Early Detection
Figure 2
PFAA profiles of cancer patients.
The results of the Mann-Whitney U-test (A) and receiver-operator characteristic (ROC) curve analysis (B) are indicated. A. Colored cells indicate that the concentration or ratio is increased in cancer patients at p<0.001 (red), p<0.01 (orange), and p<0.05 (pink), and decreased in cancer patients at p<0.001 (blue), p<0.01(sky blue), and p<0.05 (light blue), respectively. B. Axes show the AUC of ROC for each amino acid to discriminate patients from controls. Concentrations and ratios of each cancer patient and the pooled data set are indicated, respectively. Black bold lines indicate the point where the AUC of ROC = 0.5.