Gene Bionetwork Analysis of Ovarian Primordial Follicle Development
Figure 2
The ovary gene co-expression network and corresponding gene modules.
A topological overlap matrix of the gene co-expression network consisting of the 1540 genes regulated by the various growth factors. Genes in the rows and columns are sorted by an agglomerative hierarchical clustering algorithm (see Methods). The different shades of color signify the strength of the connections between the nodes (from white signifying not significantly correlated to red signifying highly significantly correlated). The hierarchical clustering (top) and the topological overlap matrix strongly indicate highly interconnected subsets of genes (modules). Modules identified are colored along both column and row and are boxed. The number of genes in each module is listed as size of module.