A Novel Replication-Competent Vaccinia Vector MVTT Is Superior to MVA for Inducing High Levels of Neutralizing Antibody via Mucosal Vaccination
Figure 2
Virulence of MVTT-S in mice after i.n. inoculation.
Groups of six mice were inoculated with MVTT-S, MVA-S or PBS twice at a dose of 106 PFU at a three-week interval. The body weight of animals was measured overtime post inoculation. The average values (±standard error) of body weight are plotted for each group of animals. The arrow indicates the time of each viral inoculation.