Cellular Growth and Mitochondrial Ultrastructure of Leishmania (Viannia) braziliensis Promastigotes Are Affected by the Iron Chelator 2,2-Dipyridyl
Figure 2
Cytotoxicity of 2,2-dipyridyl to L. (V.) braziliensis after 24 and 48 h.
Parasites were incubated at 25°C in Schneider's medium in the absence (control) or presence of 25, 50, 100, 140 or 180 µM 2,2-dipyridyl. The graphs illustrate the relationship between time of incubation and fluorescence emitted after the reduction of resazurin. Bars represent means and standard errors obtained from three independent experiments. Asterisks represent a significant reduction in fluorescence after treatment of parasites in relation to the experimental control (p<0.01, Student's T test).