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Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

Fig 2

Maximum likelihood estimates of heritability (points) and bootstrap confidence intervals (segments) for subtype B sequence.

This is shown for the BM and OU model and the GSVL and SPVL measures of viral load for the whole-genome phylogeny; for the OU model and GSVL on the phylogeny inferred only from gag, pol, and env genes (light grey box); and for several stratifications of the data, only when the size of the subset was greater than 400 (dark grey box). CH: Switzerland, NL: the Netherlands; male sex; MSM. The data used in the figure are provided as S1 Data.

Fig 2

doi: https://doi.org/10.1371/journal.pbio.2001855.g002