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Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells

Fig 2

Localization of CCL20 protein in colonic biopsies.

Immunohistochemical staining for CCL20 protein in colonic biopsies from active (UCa) or inactive (UCi) ulcerative colitis, and active (CDa) or inactive (CDi) Crohn’s disease. Healthy controls display CCL20 positivity similar to uninflamed biopsies and are not shown. Scale bars as indicated. ES = Surface epithelium, EC = Crypt epithelium, LP = Lamina propria.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0141710.g002