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99mTcO4-, Auger-Mediated Thyroid Stunning: Dosimetric Requirements and Associated Molecular Events

Figure 2

Changes in thyroid uptake 2499mTcO4.

Mice were injected with various amounts of 99mTcO4 (25 to 150 MBq). Twenty-four hours later, a standard dose of 50 MBq 99mTcO4 was injected to determine the capacity of the thyroid to take up the radioisotope. The figure represents the relationship between the initial absorbed dose to the thyroid (in Gy) and the percent change in 99mTcO4 uptake 24 hours later.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0092729.g002