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Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea

Fig 14

TCA cycle gene present in ANME archaea.

(A) Schematic of the enzymes and reactants in the partial oxidative and reductive TCA cycles in ANME that lead to 2-oxoglutarate for the purpose of producing anabolic intermediates for biosynthesis. Reductive pathway shown in blue; oxidative pathway shown in red. (B) Colored boxes represent presence of various TCA cycle genes in ANME genomes. Missing genes are represented by gray boxes with diagonal line fill. Numbers in the second column represent genome completeness. When genes are together in a gene cluster, their boxes are displayed fused together. Note: Some steps can be carried out by multiple different enzyme systems. Gene accession numbers can be found in S2 Data. ANME, anaerobic methanotrophic; TCA, tricarboxylic acid.

Fig 14

doi: https://doi.org/10.1371/journal.pbio.3001508.g014