Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution
Figure 10
Gene swapping in Cluster B1 genomes.
A. Alignment of the Cluster B1 genomes shows a swap of genes between Chah genes 63 and 73 and their homologues. Segments of genome maps of phages Chah, Colbert, UncleHowie and Puhltonio are shown with regions of nucleotide similarity identified by colored shading between them; shading reflects degrees of similarity with the color spectrum, such that violet is most similar and red the least similar. B. A reduction in GC% content in an intergenic region between Colbert genes 63 and 64 and UncleHowie genes 63 and 64 suggests the presence of regulatory elements notwithstanding the swapping of the downstream genes.