Variability of CSF Alzheimer’s Disease Biomarkers: Implications for Clinical Practice
Figure 1
CSF levels by analysis and marker.
Results are frequencies and mean (SD) for each CSF marker on the left (A) for CSF intralaboratory analyses and on the right (B) for CSF interlaboratory analyses. The solid line represents the mean CSF levels. Analysis 1 is routine practice and analysis 2 is performed as part of the LeARN study. CSF = cerebrospinal fluid, Aβ = amyloid beta, t-tau = total tau, p-tau = phosphorylated tau. **P<0.001, *p<0.05 compared to CSF analysis 1 or lab 1.