Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis
Figure 1
Selective distribution of Cnr2 in the adipose tissue and regulation during obesity.
A, Time course of Cnr2 and Emr1 expression in the epididymal adipose tissue of obese ob/ob and HFD-fed WT mice and corresponding body weight. B, Cnr2 expression was quantified in the SVF and adipocyte fraction of ob/ob and ob+/ob mice. C, Time course of Cnr2 expression in the liver of obese ob/ob and HFD-fed WT mice. D, Cnr2 expression was quantified in the non parenchymal and parenchymal liver cell fractions of ob/ob and ob+/ob mice. *p<0.05 for ob/ob vs age-matched ob+/ob mice or for HFD-fed vs age-matched ND-fed mice.