Increased oxidative stress in elderly leprosy patients is related to age but not to bacillary load
Fig 1
Evaluation of oxidative stress in serum samples.
(A) Concentration of NO in the serum of patients and healthy volunteers. Horizontal short lines represent mean of each group. Analysis of variance was performed by one-way ANOVA followed by Tukey’s multiple comparison test. Graphs represent means ± SD of serum protein carbonyl group concentration and a Mann/Whitney U-test for continuous variables was performed to evaluate significant differences between groups of (B) L-Lep patients (Y n = 12 and E n = 13), (C) T-Lep patients (Y n = 12 and E n = 15) and (D) healthy volunteers (Y n = 10 and E n = 15), each circle represents an individual. (E) Serum protein carbonyl group concentration, each square represents an individual (same n above) and the short horizontal lines represent means. Analysis was performed by one-way ANOVA followed by Tukey’s multiple comparison test. *P < 0.05, **P < 0.01 and ****P = 0.0001. Abbreviations: E—Elderly; Y—Young; T-Lep (paucibacillary; TT/BT patients); L-Lep (multibacillary; BL/LL patients); HV—healthy volunteers.