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Blockade of dengue virus transmission from viremic blood to Aedes aegypti mosquitoes using human monoclonal antibodies

Fig 1

Both 14c10 variants neutralize DENV-1 in low microgram per mL concentrations.

The same blood samples were used between mAbs. The y-axis value of 100 means the mAb blocks DENV infection of mosquitoes completely, relative to the negative control. The isotype control mAb binds to respiratory syncytial virus. Means and standard errors of more than two replicates are shown. The positive control (hyper-immune globulin (HIG)) is in black while tested mAbs are in gray.

Fig 1

doi: https://doi.org/10.1371/journal.pntd.0007142.g001