Low Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus
Fig 1
Phenotype comparison between G3 and G5 of JEV.
(A) CPE of BHK-21 cells caused by P3 and XZ0934 strains at different times, included rounding, and cell rupture. (B) Plaque phenotype of the JEV P3 and XZ0934 strains in BHK-21 cells after 3 days of infection. (C) Relative multiplication characteristics of the P3 and XZ0934 strains in BHK-21 cells. Cells were plated into 6-well culture plates and infected with the JEV strains at a MOI of 0.01pfu /cell. Values represent the mean and standard deviation from three independent experiments.