Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function
Figure 1
Genetic association and LD distribution of the MPPED2 gene locus in European and African ancestry populations.
Regional association plots in the CKDGen European ancestry discovery analysis (N = 74,354) (A) and in the CARe African ancestry discovery analysis (N = 8,110) (B). LD structure: comparison between the HapMap release II – CEU and YRI samples in the region included within +/−100 kb from the target SNP rs3925584 identified in the CKDGen GWAS. The green circle highlights a stream of high LD connecting the two blocks, indicating the presence of common haplotypes (C).