Genetic Association Study Identifies HSPB7 as a Risk Gene for Idiopathic Dilated Cardiomyopathy
Figure 1
Linkage disequilibrium (LD) structure of HSPB7 genomic region and association results.
(A) LD measurement (r2) of HapMap data on CEU samples (release #22) in relation to rs1739843. On each side of the SNP, 100 kb were analyzed and plotted (n = 138 SNPs). (B) SNPs (n = 9, Table S1; *, two SNPs) in HSPB7 gene region on the 50K gene-centric human CVD bead chip after quality control and λ-corrected association results in 664 DCM cases and 1,874 controls. Plots were generated by using the SNAP tool [33].