Dexamethasone treatment of murine auditory hair cells and cochlear explants attenuates tumor necrosis factor-α-initiated apoptotic damage
Fig 1
Effects of TNF-α and dexamethasone (DEX) on cell viability (A) Dose-dependent cell viability of HEI-OC1 cells exposed to TNF-α. Cells were treated with various concentrations of TNF-α (0–20 ng/ml) for 24 h and viability was measured using a CCK-8 assay. (B) Cell viability of HEI-OC1 cells at various concentrations of DEX. Cells were treated with DEX (0–20 nM) for 6 h or 24 h and viability was measured using a CCK-8 assay. All values are expressed as the means ± SE for four independent experiments, expressed as a percentage of untreated control value. * P < 0.05, ** P < 0.01, *** P < 0.001 compared with untreated control.