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Genomic mutation profile in progressive chronic lymphocytic leukemia patients prior to first-line chemoimmunotherapy with FCR and rituximab maintenance (REM)

Fig 1

Incidence and distribution of mutations in the 26 analyzed genes and genetic markers in the REM cohort.

Rows correspond to sequenced genes and genetic features; columns represent individual patients with CLL. (Figure done with oncoprint tool in cBioPortal). Colour code: IGHV: red, unmutated IGHV, blue: mutated IGHV, orange: no data. Genetic alterations: green, missense mutation; black, truncating mutation; light blue, deletion; red, gain.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0257353.g001