Effect of moderate elevated intra-abdominal pressure on lung mechanics and histological lung injury at different positive end-expiratory pressures
Fig 1
Experimental model study protocol.
After instrumentation and a 30-min stabilization period animals underwent measurements at H0 with PEEP 5 and no elevated intraabdominal pressure (IAP). Thereafter the intraabdominal balloon was filled with water up to an IAP of 10 mmHg. Animals were randomized afterwards to the three different groups with group A: PEEP 5 cmH2O, group B: PEEP 10 cmH2O and group C: PEEP 15 cmH2O. The IAP was held at 10 mmHg for 6 hours.