The STK33-Linked SNP rs4929949 Is Associated with Obesity and BMI in Two Independent Cohorts of Swedish and Greek Children
Figure 1
DNA elements within and in the proximity of the rs4929949-related haplotype block.
Haplotype blocks were visualized in Haploview according to confidence intervals as described by Gabriel et al. [24]. The haplotype block containing rs4929949 is visualized in green. DNA elements from the Encyclopedia of DNA Elements (ENCODE) were visualized via the UCSC genome browser (htytp://genome.ucsc.edu/). Probable regulatory sites are indicated by acetylation of Lysine 27 on Histone H3 (H3K27ac), DNase sensitivity clusters and chromatin immunoprecipitation sequencing results (ChIP-seq).The haplotype block encompasses one probable regulatory element near the 3′ region of STK33 and lies proximally to an additional upstream regulatory element.