DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Figure 1
p-values of association (−log10 scale) with breast cancer risk in BRCA2 carriers for genotyped and imputed SNPs in the NEIL2 gene.
SNP rs1466785 is indicated with a purple arrow and the best causal imputed SNPs, rs804276 and rs804271 are indicated with a red arrow. Colors represent the pariwise r2. Plot generated with LocusZoom [42] (http://csg.sph.umich.edu/locuszoom/).