Summary
An experiment was carried out on spontaneous alternation in rats which was found to be increased by caffeine, and reduced by alcohol and previous exposure to the test situation. These results were interpreted in terms of a model of behaviour, developed from ideas put forward by Glanzer (1953, 1958) and Kirkby (1967).
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References
Crossland, J., Slater, P.: Effect of some drugs on the free and bound acetylcholine content of rat brain. Brit. J. Pharmacol. 33, 42–47 (1968).
Deutsch, J. A., Hamburg, M. D., Dahl, D.: Anticholinesterase induced amnesia and its temporal aspects. Science 151, 221–223 (1966a).
—, Leibowitz, S. F.: Amnesia or reversal of forgetting by anticholinesterase, depending simply on time of injection. Science 153, 1017–1018 (1966b).
—, Lutzky, H.: Memory enhancement by anticholinesterase as a function of initial learning. Nature (Lond.) 213, 742 (1967a).
—, Rocklin, K. W.: Amnesia induced by scopolamine and its temporal variations. Nature (Lond.) 216, 89–90 (1967b).
Douglas, R. J., Isaacson, R. L.: Spontaneous alternation and scopolamine. Psychonom. Sci. 4, 283–284 (1966).
Fiske, D. W., Maddie, S. R. (eds.): Function of varied experience. Homewood, Ill.: Dorssy Press 1961.
Gaddum, J. H.: Pharmacology. London: Oxford University Press 1959.
Glanzer, M.: Stimulus satiation, an explanation of spontaneous alternation and related phenomena. Psychol. Rev. 60, 257–268 (1953).
—: Curiosity, exploratory drive and stimulus satiation. Psychol. Bull. 55, 302–315 (1958).
Goodman, L. S., Gilman, A.: The pharmacological basis of therapeutics. London: Macmillan 1968.
Grollman, A.: Pharmacology and Therapeutics. London: Henry Kimpton 1962.
Kirkby, R. J.: A maturation factor in spontaneous alternation. Nature (Lond.) 215, 784 (1967).
—, Stein, D. G., Kimble, R. J., Kimble, D. F.: Effects of hippocampal lesions, and duration of sensory input on spontaneous alternation. J. comp. physiol. Psychol. 64, 342–345 (1967).
Lewis, J. J.: Pharmacology. London: E. and S. Livingstone 1962.
Parkes, W. M.: An examination of central actions characteristic of scopolamine. Psychopharmacologia (Berl.) 7, 1–19 (1965).
Ratcliffe, F.: Neurochemical effects of chronic alcohol administration in the rat. University of Nottingham: Ph. D. Thesis 1968.
Rosenzweig, M. R., Krech, D., Bennett, E. I.: A search for relations between brain chemistry and behaviour. Psychol. Bull. 57, 476–492 (1960).
Squire, L. R.: Effects of pretrial and posttrial administration of cholinergic and anticholinergic drugs on spontaneous alternation. J. comp. physiol. Psychol. 69, 69–75 (1969).
Walker, E. L.: The duration and course of reaction decrement and the influence of reward. J. comp. physiol. Psychol. 49, 167–176 (1956).
Weiner, N., Deutsch, J. A.: The temporal aspects of anticholinergic and cholinesterase induced amnesia for an appetitive habit. J. comp. physiol. Psychol. 66, 613–617 (1968).
Zeaman, D., House, B. J.: The growth and decay of reactive inhibition as measured by alternation behaviour. J. exp. Psychol. 41, 177–186 (1951).
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Cox, T. The effects of caffeine, alcohol, and previous exposure to the test situation on spontaneous alternation. Psychopharmacologia 17, 83–88 (1970). https://doi.org/10.1007/BF00402093
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DOI: https://doi.org/10.1007/BF00402093