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Rapid diagnosis of Candida albicans

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Abstract

The inhibitory action of an antibiotic isolated fromB. subtilis is studied onC. albicans, C. clausenii, C. langeronii, C. stellatoidea, andC. visvanathii, as a possible means forC. albicans rapid identification. Growth inhibition ofC. albicans by the antibiotic was observed when the yeast was preincubated on malt-agar slants, at 30° C, during 24 hours, and tested afterwards for antibiosis on Sabouraud-agar plates. No growth inhibition could be detected withC. clausenii, C. langeronii, C. stellatoidea, andC. viswanathii, under the same experimental conditions.

In support of our results are the data reported byPérez-Silva &Gil-Alvarez (1960), where 33 strains ofC. albicans tested against that antibiotic, were shown to be the only sensitive yeast amongst 68 strains of yeast from several species.

Zusammenfassung

Die Wirkung der Inhibition eines vomB. subtilis isolierten Antibiotiks wurde untersucht anC. albicans, C. clausenii, C. langeronii, C. stellatoides, undC. viswanathii als ein mögliches Mittel für die schnelle Bestimmung vonC. albicans. Wachstumsinhibition vonC. albicans durch das Antibiotik war beobachtet, wenn die Hefe an Maltose-Schrägagar vorher inokuliert, bei 30° C für 24 Std., und nachher für Antibiosis an Sabouraud Agarplatten untersucht worden ist. Keine Inhibitionswirkung konnte mitC. clausenii, C. langeronii, C. stellatoides undC. viswanathii unter den selben experimentellen Bedingungen beobachtet werden. Die Ergebnisse sind durch diejenigen vonPérez-Silva &Gil-Alvarez (1960) unterstützt, in denen 33 Stämme vonC. albicans gegen das Antibiotik getested und gezeigt worden sind, daß nurC. albicans die einzige empfindliche Hefe unter 68 Stämmen von Hefen verschiedener Arten war.

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Ramírez, C., Lanzuela, F. & Rodriguez, D. Rapid diagnosis of Candida albicans. Mycopathologia et Mycologia Applicata 40, 107–111 (1970). https://doi.org/10.1007/BF02051988

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