Abstract
WHILE it is very well known that ionizing radiations act on many substances of biological importance, such as enzymes, simple and complex proteins and nucleic acids, there is little information about the changes caused in mucopolysaccharides. It has been reported1 that solutions of hyaluronic acid after irradiation show a significant decrease of viscosity which is related to the intensity of irradiation. In examining the properties of irradiated conjugated proteins, such as nucleoproteins and mucoproteins, I have investigated the effects on the prosthetic groups of these molecules. The present communication deals with the action of X-rays on hyaluronic acid.
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References
Schoemberd, M. D., Brook, R. E., Hall, J. J., and Scheiderman, H., U.S. Atomic Energy Com., U.C.L.A., (1950), 83.
Elson, L. A., and Morgan, W. T. J., Biochem. J., 37, 1824 (1933).
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CAPUTO, A. Depolymerization of Hyaluronic Acid by X-rays. Nature 179, 1133–1134 (1957). https://doi.org/10.1038/1791133a0
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DOI: https://doi.org/10.1038/1791133a0
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