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Myoglobin-Radioimmunoassay: Erfahrungen bei der Diagnostik von Skeletmuskelerkrankungen

Myoglobin radioimmunoassay: Experience of the diagnosis of skeletal muscle disorders

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Summary

Serum myoglobin was measured by a sensitive radioimmunoassay in healthy controls and in patients with skeletal muscle disorders such as polymyositis and Duchenne type muscular dystrophy. The serum myoglobin levels were closely related to the serum creatine kinase (CK) activity, thus indicating that myoglobin is a useful adjunct in the assessment of muscle cell damage.

Zusammenfassung

Die Serum-Myoglobinkonzentration wurde mit einem empfindlichen Radioimmunoassay bei gesunden Kontrollpersonen und Patienten mit Polymyositis und progressiver Muskeldystrophie vom Typ Duchenne bestimmt. Die gemessenen Konzentrationen korrelieren eng mit der Serum-Kreatin-Kinase, so daß die Myoglobinkonzentration im Serum als nützlicher Parameter bei der Beurteilung von Muskelzellschäden herangezogen werden kann.

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Authors and Affiliations

  1. Neurologische Universitätsklinik, JosefSchneider-Straße 11, D-8700, Würzburg, Bundesrepublik Deutschland

    Wolfgang R. Kießling & Karl W. Pflughaupt

Authors
  1. Wolfgang R. Kießling
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  2. Karl W. Pflughaupt
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Herrn Prof. Dr. H. G. Mertens zum 60. Geburtstag gewidmet

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Kießling, W.R., Pflughaupt, K.W. Myoglobin-Radioimmunoassay: Erfahrungen bei der Diagnostik von Skeletmuskelerkrankungen. Arch Psychiatr Nervenkr 230, 49–54 (1981). https://doi.org/10.1007/BF00343766

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  • DOI: https://doi.org/10.1007/BF00343766

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