Skip to main content
SpringerLink
Log in

DOPA decarboxylase activity in a transplantable hamster melanoma

  • Kurze Mitteilungen
  • Published:
Experientia Aims and scope Submit manuscript

Résumé

Une activité considérable de la 3,4-dihydroxyphénylealanine (DOPA) décarboxylase a été démontrée chez un transplantable mélanome malin du hamster. Après l'injection intrapéritonéale du précurseur de la dopamine, l'amine nouveau-formée était trouvée dans toutes les tumeurs. L'inhibition de la DOPA décarboxylase par traitement des hamsters avec α-méthyle-DOPA n'a pas influé sur le progrès des tumeurs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. J. Duchoň andV. Gregora, Clin. chim. Acta7, 443 (1962).

    Article  Google Scholar 

  2. K. N. F. Shaw, A. McMillan, andM. D. Armstrong, J. biol. Chem.226, 225 (1957).

    Google Scholar 

  3. A. B. Lerner andTh. B. Fitzpatrick, Physiol. Rev.30, 91 (1950).

    Article  CAS  Google Scholar 

  4. T. Šalamon andH. Storck, Arch. klin. exp. Derm.216, 161 (1963).

    Article  Google Scholar 

  5. A. G. Everson Pearse,Histochemistry: Theoretical and Applied (Churchill, London 1960), p. 919.

    Google Scholar 

  6. Å. Bertler, A. Carlsson, andE. Rosengren, Acta physiol. scand.44, 273 (1958).

    Article  CAS  Google Scholar 

  7. A. Carlsson andB. Waldeck, Acta physiol. scand.44, 293 (1958).

    Article  CAS  Google Scholar 

  8. R. Håkanson, Biochem. Pharmacol.12, 1289 (1963).

    Article  Google Scholar 

  9. R. Håkanson andCh. Owman, J. Neurochem., in press.

  10. R. Håkanson andH. Möller, Acta dermat.-venereol.43, 552 (1963).

    Google Scholar 

  11. R. Håkanson andH. Möller, Acta dermat.-venereol.43, 485 (1963).

    Google Scholar 

  12. R. Håkanson, Exper.17, 402 (1961).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Pharmacology, Dermatology and Pathology, University of Lund, Sweden

    R. Håkanson, H. Möller & N. G. Stormby

Authors
  1. R. Håkanson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Möller
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. G. Stormby
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This study was supported by grants from Riksföreningen mot cancer, Stockholm, and from the Léonie Deshayes' Foundation, Lund. Melanoma-bearing Syrian hamsters were generously supplied by Prof.H. Storck, Zürich (Switzerland). The supply of α-methyl DOPA from Merck, Sharp and Dohme (USA) is gratefully acknowledged.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Håkanson, R., Möller, H. & Stormby, N.G. DOPA decarboxylase activity in a transplantable hamster melanoma. Experientia 21, 265–266 (1965). https://doi.org/10.1007/BF02297017

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02297017

Keywords

Search

Navigation