Two new phenolic glycosides, 2-(2-((1E,6Z)-3,8-dihydroxy-3,7-dimethylocta-1,6-dien-1-yl)-4-hydroxy-6-methylphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (1) and 2-(2-((E)-2-(2,6-dimethyl-2,3,4,7-tetrahydrooxepin-2-yl)vinyl)-4-hydroxy-6-methylphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (2) were isolated from Thalictrum scabrifolium. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited anti-TMV activities with inhibition rates of 34.1 and 35.9% at a concentration of 20 μM/mL, respectively, compared with 35.3% for the positive control ningnanmycin.
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This project was supported by the Key Laboratory of Yunnan Provincial Department of Education (2022HD021), the Foundation of Yunnan Basic Research Youth Program (2019FD119), and the Foundation of Yunnan Innovative Research Team (2019HC020).
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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2023, pp. 568–571.
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Zheng, JN., Yang, M., Xiong, RF. et al. Two New Phenolic Glycosides from Thalictrum scabrifolium and Their Anti-TMV Activities. Chem Nat Compd 59, 675–679 (2023). https://doi.org/10.1007/s10600-023-04084-7
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DOI: https://doi.org/10.1007/s10600-023-04084-7