Skip to main content

Advertisement

SpringerLink
Log in

Anti-Ri antibody positive opsoclonus-myoclonus in a male patient with breast carcinoma

  • ORIGINAL COMMUNICATION
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Abstract.

A 65-year-old male patient developed truncal ataxia, opsoclonus and myoclonus. In the serum anti-Ri antibodies were found, which led to the detection of a small adenocarcinoma of the breast. Other prominent clinical features were an excessive startle response and behavioral disorders, such as anxiety and impatience. These features suggest an immune response against both Nova-1 and Nova-2 antigens throughout the central nervous system.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Department of Neurology, J3R-166, Leiden University Medical Center, P. O. Box 9600, 2300 RC Leiden, The Netherlands. pwwirtz@lumc.nl, , , , , , NL

    Paul W. Wirtz, Jorrit I. Hoff, Gert Jan Lammers & Jan J. Verschuuren

  2. Department of Neuro-Oncology, Dr. Daniel den Hoed Cancer Center, University Hospital Dijkzigt, Rotterdam, The Netherlands, , , , , , NL

    Peter A. E. Sillevis Smitt & Bertie de Leeuw

  3. Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands, , , , , , NL

    Sjoerd G. van Duinen

Authors
  1. Paul W. Wirtz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter A. E. Sillevis Smitt
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jorrit I. Hoff
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Bertie de Leeuw
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Gert Jan Lammers
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Sjoerd G. van Duinen
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Jan J. Verschuuren
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 20 March 2002, Received in revised form: 20 June 2002, Accepted: 25 June 2002

Correspondence to P. W. Wirtz

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wirtz, P., Sillevis Smitt, P., Hoff, J. et al. Anti-Ri antibody positive opsoclonus-myoclonus in a male patient with breast carcinoma. J Neurol 249, 1710–1712 (2002). https://doi.org/10.1007/s00415-002-0913-z

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-002-0913-z

Search

Navigation