The MICs of talampicillin against Staphylococcus aureus, Escherichia coli, Klebsiellaand Pseudomonas aeruginosa were similar to those of ampicillin.
To evaluate the clinical effect of talampicillin, the treatment with the drug was made in 36 patients of infections including 24 of respiratory infections, 11 of urinary tract infections and one of biliary infection. One patient was cured with excellent clinical effect, 24 were good, 3 were fair, 3 were failure and 5 were undetermined.
As to the side effects of the drug, nausea and discomfort of the epigastrium were noticed in one patient and rash in one patient, respectively, during the treatment.