Issue 23, 1992

Peptides from Australian frogs. Structures of the caerins and caeridin 1 from Litoria splendida

Abstract

Seven peptides have been isolated from the parotoid and rostral glands of the Australian green tree frog Litoria splendida. These include caerulein (a known hypotensive toxin), and six new compounds named caerin 1.1 (M, 2582), 1.1.1 (2412), 1.1.2 (2299), 2.1 (2392), 3.1 (2382) and caeridin 1 (1139). The primary structures of the peptides have been determined by FAB mass spectrometric methods, and confirmed by automated sequencing. The major peptides have been synthesised using t-BOC (N-tert-butoxycarbonyl)N-protection and a p-methylbenzhydrylamine support.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1992, 3173-3178

Peptides from Australian frogs. Structures of the caerins and caeridin 1 from Litoria splendida

D. J. M. Stone, R. J. Waugh, J. H. Bowie, J. C. Wallace and M. J. Tyler, J. Chem. Soc., Perkin Trans. 1, 1992, 3173 DOI: 10.1039/P19920003173

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements