Skip to main content

Advertisement

Log in

Steatosis in chronic hepatitis C: fuel for overproduction of oxidative stress?

  • Editorial
  • Published:
Journal of Gastroenterology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. PA Cerutti BF Trump (1991) ArticleTitleInflammation and oxidative stress in carcinogenesis Cancer Cells 3 1–7 Occurrence Handle2025490

    PubMed  Google Scholar 

  2. D Dreher AF Junod (1996) ArticleTitleRole of oxygen free radicals in cancer development Eur J Cancer 32 30–8

    Google Scholar 

  3. B Chance H Sies A Boveris (1979) ArticleTitleHydroperoxide metabolism in mammalian organs Physiol Rev 59 527–605 Occurrence Handle37532

    PubMed  Google Scholar 

  4. PA Cerutti (1994) ArticleTitleOxy-radicals and cancer Lancet 344 862–3 Occurrence Handle7916406

    PubMed  Google Scholar 

  5. H Wiseman B Halliwell (1996) ArticleTitleDamage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer Biochem J 313 17–29 Occurrence Handle8546679

    PubMed  Google Scholar 

  6. F Farinati R Cardin N De Maria G Della Libera C Marafin E Lecis et al. (1995) ArticleTitleIron storage, lipid peroxidation and glutathione turnover in chronic anti-HCV positive hepatitis J Hepatol 22 449–56

    Google Scholar 

  7. V Paradis P Mathurin M Kollinger F Imbert-Bismut F Charlotte A Piton et al. (1997) ArticleTitleIn situ detection of lipid peroxidation in chronic hepatitis C: correlation with pathological features J Clin Pathol 50 401–6 Occurrence Handle9215123

    PubMed  Google Scholar 

  8. K Moriya K Nakagawa T Santa Y Shintani H Fujie H Miyoshi et al. (2001) ArticleTitleOxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocellular carcinogenesis Cancer Res 61 4365–70 Occurrence Handle11389061

    PubMed  Google Scholar 

  9. M Okuda K Li MR Beard LA Showalter F Scholle SM Lemon et al. (2002) ArticleTitleMitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein Gastroenterology 122 366–75 Occurrence Handle11832451

    PubMed  Google Scholar 

  10. Kitase A, Hino K, Furutani T, Okuda M, Gondo T, Hidaka I, et al. In situ detection of oxidized n-3 polyunsaturated fatty acids in chronic hepatitis C: correlation with hepatic steatosis. J Gastroenterol 2005:617–24

  11. L Fartoux O Chazouilleres D Wendum R Poupon L Serfaty (2005) ArticleTitleImpact of steatosis on progression of fibrosis in patients with mild hepatitis C Hepatology 41 82–7 Occurrence Handle15690484

    PubMed  Google Scholar 

  12. JD Collier T Woodall DG Wight S Shore AE Gimson GJ Alexander (2005) ArticleTitlePredicting progressive hepatic fibrosis stage on subsequent liver biopsy in chronic hepatitis C virus infection J Viral Hepat 12 74–80 Occurrence Handle15655051

    PubMed  Google Scholar 

  13. L Castera C Hezode F Roudot-Thoraval A Bastie ES Zafrani JM Pawlotsky et al. (2003) ArticleTitleWorsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies Gut 52 288–92 Occurrence Handle12524415

    PubMed  Google Scholar 

  14. HM Patton K Patel C Behling D Bylund LM Blatt M Vallee et al. (2004) ArticleTitleThe impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients J Hepatol 40 484–90 Occurrence Handle15123364

    PubMed  Google Scholar 

  15. G Perlemuter A Sabile P Letteron Topilco M-E Samson-Bouna Y Chretien et al. (2002) ArticleTitleHepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis FASEB J 16 185–94 Occurrence Handle11818366

    PubMed  Google Scholar 

  16. Y Shintani H Fujie H Miyoshi T Tsutsumi S Kimura K Moriya et al. (2004) ArticleTitleHepatitis C virus and diabetes: direct involvement of the virus in the development of insulin resistance Gastroenterology 126 840–8 Occurrence Handle14988838

    PubMed  Google Scholar 

  17. K Moriya T Todoroki T Tsutsumi H Fujie Y Shintani H Miyoshi et al. (2001) ArticleTitleIncrease in the concentration of carbon 18 monounsaturated fatty acids in the liver with hepatitis C: analysis in transgenic mice and humans Biophys Biochem Res Commun 281 1207–12

    Google Scholar 

  18. Koike K, Moriya K. Metabolic aspects of hepatitis C: steatohepatitis resembling but distinct from NASH. J Gastroenterol 2005; in press

  19. B Fromenty MA Robin A Igoudjil A Mansouri D Pessayre (2004) ArticleTitleThe ins and outs of mitochondrial dysfunction in NASH Diabetes Metab 30 121–38 Occurrence Handle15223984

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Koike, K. Steatosis in chronic hepatitis C: fuel for overproduction of oxidative stress?. J Gastroenterol 40, 664–665 (2005). https://doi.org/10.1007/s00535-005-1626-8

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00535-005-1626-8

Keywords

Navigation