In:
Journal of Bioinformatics and Computational Biology, World Scientific Pub Co Pte Ltd, Vol. 03, No. 02 ( 2005-04), p. 491-526
Abstract:
Biological sequences and structures have been modelled using various machine learning techniques and abstract mathematical concepts. This article surveys methods using Hidden Markov Model and functional grammars for this purpose. We provide a formal introduction to Hidden Markov Model and grammars, stressing on a comprehensive mathematical description of the methods and their natural continuity. The basic algorithms and their application to analyzing biological sequences and modelling structures of bio-molecules like proteins and nucleic acids are discussed. A comparison of the different approaches is discussed, and possible areas of work and problems are highlighted. Related databases and softwares, available on the internet, are also mentioned.
Type of Medium:
Online Resource
ISSN:
0219-7200
,
1757-6334
DOI:
10.1142/S0219720005001077
Language:
English
Publisher:
World Scientific Pub Co Pte Ltd
Publication Date:
2005
SSG:
12
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