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  • 1
    Online Resource
    Online Resource
    Singapore : Springer Singapore | Singapore : Imprint: Springer
    Keywords: Geography. ; Sustainable development. ; Architecture. ; Sustainable architecture. ; Sociology, Urban.
    Description / Table of Contents: Part I. Theory and Development of Green Village and Town Construction -- Theory and Innovation of Green Construction of Village and Town -- Evolution and Development of Green Construction of Village and Town -- Pattern and Mechanism of Green Construction of Village and Town -- Green Construction Community of Village and Town -- Part II. Plan and Construction Methods of Green Village and Town -- Plan Compilation of Green Construction of Village and Town -- Green Construction of Environmental Infrastructure of Village and Town -- Construction and Renovation of Green Building in Village and Town -- Part III. Evaluation of Plan and Construction of Green Village and Town -- Evaluation of Green Village and Town Plan -- Evaluation of Environmental Infrastructure Construction of Green Village and Town -- Evaluation of Green Building Construction of Village and Town -- Comprehensive Evaluation of Plan and Construction of Green Village and Town -- Appendix. .
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource(XXII, 466 p. 115 illus., 69 illus. in color.)
    Edition: 1st ed. 2021.
    ISBN: 9789811620980
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 2602-2604 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Pressure-induced shift of fluorescence emission in garnets and other oxides is investigated for applications as optical pressure sensors. We report high pressure studies on the fluorescence emission from neodymium-doped yttrium aluminum perovskite (Nd3+:YAlO3) to 80 GPa at room temperature. Unusual nonlinear blueshift of wavelength with pressure was found for several fluores cence peaks in the wavelength region of 850–900 nm. These peaks are identified as the lines associated with transition Nd3+:4F3/2→4I9/2 in YAlO3. The blueshift of these emissions is compared with the redshift of the same system in neodymium-doped yttrium aluminum garnet (Nd3+:Y3Al5O12). The shift with pressure is related to the change in the Stark level splitting with pressure. In view of the strong red emission from diamond anvils at ultrahigh pressures, this near infrared emission of Nd3+:YAlO3 holds promise as an ultrahigh pressure sensor. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Molecular and Cellular Endocrinology 74 (1990), S. 221-228 
    ISSN: 0303-7207
    Keywords: Integrin superfamily ; Interleukin-1 ; Osteopontin mRNA
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 34 (1999), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Transforming growth factor-betas (TGF-βs) and bone morphogenetic proteins (BMPs), members of a TGF-β superfamily, are known to play an important role in osteogenic cell differentiation and consequently bone formation. We have reported previously that periodontal ligament (PDL) cells differentiate and form mineralized nodules when cultured in the presence of dexamethasone (Dex), β-glycerophosphate (GP) and ascorbic acid (AA). To understand the roles of TGF-β isoforms (TGF-β1, 2 and 3) and TGF-β type 1 receptors (activin receptor-like kinase (ALK)-2, -3, -5 and -6) in PDL cell differentiation, their expression was investigated using Northern blot analysis. Rat PDL cells, derived from coagulum in the tooth socket, were cultured in the presence of Dex (5 μM), GP (10 mM) and AA (50 μg/ml) for up to 21 d. Total RNA was isolated from PDL cells after 0, 7, 14 and 21 d and used for Northern blot analysis of mRNAs for matrix proteins, TGF-β isoforms and their receptors using 32P-labeled cDNAs as probes. Four stages showing distinct morphological characteristics and matrix expression during development of mineralized nodules were identified. Type I collagen (Col I) and SPARC (secreted protein. acidic and rich in cysleine) mRNAs were expressed at the confluent stage, but decreased during the mineralization stage. Osteopontin (OPN) and alkaline phosphatase (ALP) transcripts were initially observed at multilayer stage, while bone sialoprotein (BSP) and osteocalcin (OC) at the nodule stage and all 4 were expressed thereafter. TGF-β1 mRNA expression increased with the progression of PDL cell differentiation, while a relatively high level of TGF-β3 transcript decreased slightly during their differentiation. TGF-β2 mRNA was not expressed. The expression of TGFβ-RI mRNA decreased, whereas that of TGFβ-RIII increased dramatically with PDL cell differentiation. TGFβ-RII gene activities remained high throughout all stages. ALK-2, ALK-3 and ALK-6 mRNA expression increased with the progression of PDL cell differentiation, suggesting that these receptors may play important roles in Dex-induced PDL cell differentiation and mineralized nodule formation.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1615-5947
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2013-03-20
    Description: Background: The proceeding of blood pressure (BP) from normal level to the hypertension has been found to be associated with increased cardiovascular events and multiple vascular risk factors. However, whether the process is associated with increased carotid atherosclerotic plaque per se or not is still unclear. Methods: Nine hundred and forty-two participants aged from 46 to 75 were enrolled from community population in Southern China. Their metabolic risk factors, carotid intima-media thickness (cIMT) and atherosclerotic plaque formation were analyzed and stratified by different blood pressure levels according to JNC-7 or ESH/ESC-2007 classification. Results: From low BP level to higher BP level, multiple metabolic risk factors increased linearly. Prehypertension in JNC-7 classification (or normal BP and high normal BP in ESH/ESC-2007 classification) was correlated with thicker cIMT and more plaque formation than normotension (or optimal BP) (p 〈 0.001). After adjusting multiple metabolic factors, the differences were still significant (p 〈 0.05). Furthermore, prehypertensive participants had a trend to be thicker carotid IMT (OR and its 95% CI: 1.65, 0.97-2.82, p = 0.067) and significantly higher carotid plaque occurrence (OR and its 95% CI: 2.36, 1.43-3.88, p = 0.001) than normotensive ones. However, there was no significant difference of cIMT and plaque formation between normal BP and high normal BP (p 〉 0.05). Thus, we concluded that plaque formation in prehypertension was as significant as that in hypertension. Conclusion: Prehypertension is associated with significantly increased carotid atherosclerotic plaque and is a primary stratify risk factor for carotid atherosclerosis which could cause ischemic stroke in middle-aged and elderly population in Southern China.
    Electronic ISSN: 1471-2261
    Topics: Medicine
    Published by BioMed Central
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  • 7
    Publication Date: 2015-05-06
    Description: Crystal Growth & Design DOI: 10.1021/acs.cgd.5b00327
    Print ISSN: 1528-7483
    Electronic ISSN: 1528-7505
    Topics: Chemistry and Pharmacology , Geosciences , Physics
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  • 8
    Publication Date: 2013-11-16
    Description: Hepatocellular carcinoma (HCC) is one of the most prevalent cancers and is rising in incidence worldwide. The molecular mechanisms leading to the development of HCC are complex and include both genetic and epigenetic events. To determine the relative contribution of these alterations in liver tumorigenesis, we evaluated epigenetic modifications at both global and gene specific levels, as well as the mutational profile of genes commonly altered in liver tumors. A mouse model of fibrosis-associated liver cancer that was designed to emulate cirrhotic liver, a prevailing disease state observed in most humans with HCC, was used. Tumor and non-tumor liver samples from B6C3F1 mice treated with N -nitrosodiethylamine (DEN; a single ip injection of 1 mg/kg at 14 days of age) and carbon tetrachloride (CCl 4 ; 0.2 ml/kg, 2 times/week ip starting at 8 weeks of age for 14 weeks), as well as corresponding vehicle control animals, were analyzed for genetic and epigenetic alterations. H-ras , Ctnnb1 , and Hnf1α genes were not mutated in tumors in mice treated with DEN+CCl 4 . In contrast, the increased tumor incidence in mice treated with DEN+CCl 4 was associated with marked epigenetic changes in liver tumors and non-tumor liver tissue, including demethylation of genomic DNA and repetitive elements, a decrease in histone 3 lysine 9 trimethylation (H3K9me3), and promoter hypermethylation and functional down-regulation of Riz1, a histone lysine methyltransferase tumor suppressor gene. Additionally, the reduction in H3K9me3 was accompanied by increased expression of long interspersed nucleotide elements (LINE) 1 and short interspersed nucleotide elements (SINE) B2, which is an indication of genomic instability. In summary, our results suggest that epigenetic events, rather than mutations in known cancer-related genes, play a prominent role in increased incidence of liver tumors in this mouse model of fibrosis-associated liver cancer. © 2013 Wiley Periodicals, Inc.
    Print ISSN: 0020-7136
    Electronic ISSN: 1097-0215
    Topics: Biology , Medicine
    Published by Wiley-Blackwell
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  • 9
    Publication Date: 2013-05-01
    Description: Top–down fabrication of sub-nanometre semiconducting nanoribbons derived from molybdenum disulfide sheets Nature Communications 4, 1776 (2013). doi:10.1038/ncomms2803 Authors: Xiaofei Liu, Tao Xu, Xing Wu, Zhuhua Zhang, Jin Yu, Hao Qiu, Jin-Hua Hong, Chuan-Hong Jin, Ji-Xue Li, Xin-Ran Wang, Li-Tao Sun & Wanlin Guo
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2017-12-13
    Description: Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle, Published online: 12 December 2017; doi:10.1038/s41598-017-17825-w Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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