GLORIA — GEOMAR Library Ocean Research Information Access

1

Online-Ressource

Effect of Spacer Layer Thickness on Energy Level Width Narrowing in GaInAs/InP Resonant Tunneling Diodes Grown by Organo-Metallic Vapor Phase Epitaxy

Takashi Oobo, Takashi Oobo ; Riichiro Takemura, Riichiro Takemura ; Ken Sato, Ken Sato ; [weitere]

IOP Publishing ; 1998

In: Japanese Journal of Applied Physics Vol. 37, No. 2R ( 1998-02-01), p. 445-

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In: Japanese Journal of Applied Physics, IOP Publishing, Vol. 37, No. 2R ( 1998-02-01), p. 445-

Kurzfassung: We studied the effect of spacer layer thickness on the resonant level width in resonant tunneling diodes (RTDs). GaInAs/InP RTDs were fabricated with various spacer layer thicknesses using organo-metallic vapor phase epitaxy, and the resonant level width was estimated. As a result, the resonant level width was found to decrease with increasing spacer layer thickness. To discuss this tendency, a theoretical model of the interface fluctuation between spacer layers and electrodes, caused by the random distribution of the impurity ions in electrodes, was proposed.

Materialart: Online-Ressource

ISSN: 0021-4922 , 1347-4065

URL: Article

DOI: 10.1143/JJAP.37.445

RVK:

UA 4210.1

RVK:

UA 4210.2

RVK:

UA 4210

Sprache: Unbekannt

Verlag: IOP Publishing

Publikationsdatum: 1998

ZDB Id: 218223-3

ZDB Id: 797294-5

ZDB Id: 2006801-3

ZDB Id: 797295-7

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2

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Precision and Safety of an Intravascular Temperature Management System for Postcardiac Arrest Syndrome Patients: A Multicenter Clinical Trial (COOL-ARREST JP)

Maekawa, Tsuyoshi ; Kaneda, Kotaro ; Tsuruta, Ryosuke ; [weitere]

Mary Ann Liebert Inc ; 2020

In: Therapeutic Hypothermia and Temperature Management Vol. 10, No. 3 ( 2020-09-01), p. 179-185

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In: Therapeutic Hypothermia and Temperature Management, Mary Ann Liebert Inc, Vol. 10, No. 3 ( 2020-09-01), p. 179-185

Materialart: Online-Ressource

ISSN: 2153-7658 , 2153-7933

URL: Article

DOI: 10.1089/ther.2019.0046

Sprache: Englisch

Verlag: Mary Ann Liebert Inc

Publikationsdatum: 2020

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3

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Nitrification and its influence on biogeochemical cycles from the equatorial Pacific to the Arctic Ocean

Shiozaki, Takuhei ; Ijichi, Minoru ; Isobe, Kazuo ; [weitere]

Springer Science and Business Media LLC ; 2016

In: The ISME Journal Vol. 10, No. 9 ( 2016-9), p. 2184-2197

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In: The ISME Journal, Springer Science and Business Media LLC, Vol. 10, No. 9 ( 2016-9), p. 2184-2197

Materialart: Online-Ressource

ISSN: 1751-7362 , 1751-7370

URL: Article

DOI: 10.1038/ismej.2016.18

Sprache: Englisch

Verlag: Springer Science and Business Media LLC

Publikationsdatum: 2016

ZDB Id: 2299378-2

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4

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, Daniel J. ; Abdel-Aziz, Amal Kamal ; Abdelfatah, Sara ; [weitere]

Informa UK Limited ; 2021

In: Autophagy Vol. 17, No. 1 ( 2021-01-02), p. 1-382

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In: Autophagy, Informa UK Limited, Vol. 17, No. 1 ( 2021-01-02), p. 1-382

Materialart: Online-Ressource

ISSN: 1554-8627 , 1554-8635

URL: Article

DOI: 10.1080/15548627.2020.1797280

Sprache: Englisch

Verlag: Informa UK Limited

Publikationsdatum: 2021

ZDB Id: 2262043-6

SSG: 12

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5

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Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Sodium–Glucose Cotransporter 2 Inhibitor Treatment: The FIDELITY Analysis

Rossing, Peter ; Anker, Stefan D. ; Filippatos, Gerasimos ; [weitere]

American Diabetes Association ; 2022

In: Diabetes Care Vol. 45, No. 12 ( 2022-12-01), p. 2991-2998

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In: Diabetes Care, American Diabetes Association, Vol. 45, No. 12 ( 2022-12-01), p. 2991-2998

Kurzfassung: Finerenone reduced the risk of kidney and cardiovascular events in people with chronic kidney disease (CKD) and type 2 diabetes in the FIDELIO-DKD and FIGARO-DKD phase 3 studies. Effects of finerenone on outcomes in patients taking sodium–glucose cotransporter 2 inhibitors (SGLT2is) were evaluated in a prespecified pooled analysis of these studies. RESEARCH DESIGN AND METHODS Patients with type 2 diabetes and urine albumin-to-creatinine ratio (UACR) ≥30 to ≤5,000 mg/g and estimated glomerular filtration rate (eGFR) ≥25 mL/min/1.73 m2 were randomly assigned to finerenone or placebo; SGLT2is were permitted at any time. Outcomes included cardiovascular composite (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure) and kidney composite (kidney failure, sustained ≥57% eGFR decline, or renal death) end points, changes in UACR and eGFR, and safety outcomes. RESULTS Among 13,026 patients, 877 (6.7%) received an SGLT2i at baseline and 1,113 (8.5%) initiated one during the trial. For the cardiovascular composite, the hazard ratios (HRs) were 0.87 (95% CI 0.79–0.96) without SGLT2i and 0.67 (95% CI 0.42–1.07) with SGLT2i. For the kidney composite, the HRs were 0.80 (95% CI 0.69–0.92) without SGLT2i and 0.42 (95% CI 0.16–1.08) with SGLT2i. Baseline SGLT2i use did not affect risk reduction for the cardiovascular or kidney composites with finerenone (Pinteraction = 0.46 and 0.29, respectively); neither did SGLT2i use concomitant with study treatment. CONCLUSIONS Benefits of finerenone compared with placebo on cardiorenal outcomes in patients with CKD and type 2 diabetes were observed irrespective of SGLT2i use.

Materialart: Online-Ressource

ISSN: 0149-5992 , 1935-5548

URL: Article

DOI: 10.2337/dc22-0294

Sprache: Englisch

Verlag: American Diabetes Association

Publikationsdatum: 2022

ZDB Id: 1490520-6

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6

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The Japanese Society for Apheresis clinical practice guideline for therapeutic apheresis

Abe, Takaya ; Matsuo, Hidenori ; Abe, Ryuzo ; [weitere]

Wiley ; 2021

In: Therapeutic Apheresis and Dialysis Vol. 25, No. 6 ( 2021-12), p. 728-876

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In: Therapeutic Apheresis and Dialysis, Wiley, Vol. 25, No. 6 ( 2021-12), p. 728-876

Kurzfassung: Most of the diseases for which apheresis therapy is indicated are intractable and rare, and each patient has a different background and treatment course prior to apheresis therapy initiation. Therefore, it is difficult to conduct large‐scale randomized controlled trials to secure high‐quality evidence. Under such circumstances, the American Society for Apheresis (ASFA) issued its guidelines in 2007, which were repeatedly revised until the latest edition in 2019. The ASFA guidelines are comprehensive. However, in the United States, a centrifugal separation method is mainly used for apheresis, whereas the mainstream procedure in Japan is the membrane separation method. The target diseases and their backgrounds are different from those in Japan. Due to these differences, the direct adoption of the ASFA guidelines in Japanese practice creates various problems. One of the features of apheresis in Japan is the development of treatment methods using hollow‐fiber devices such as double filtration plasmapheresis (DFPP) and selective plasma exchange and adsorption‐type devices such as polymyxin B‐immobilized endotoxin adsorption columns. Specialists in emergency medicine, hematology, collagen diseases/rheumatology, respiratory medicine, cardiovascular medicine, gastroenterology, neurology, nephrology, and dermatology who are familiar with apheresis therapy gathered for this guideline, which covers 86 diseases. In addition, since apheresis therapy involves not only physicians but also clinical engineers, nurses, dieticians, and many other medical professionals, this guideline was prepared in the form of a worksheet so that it can be easily understood at the bedside. Moreover, to the clinical purposes, this guideline is designed to summarize apheresis therapy in Japan and to disseminate and further develop Japanese apheresis technology to the world. As diagnostic and therapeutic techniques are constantly advancing, the guidelines need to be revised every few years. In order to ensure the high quality of apheresis therapy in Japan, both the Japanese Society for Apheresis Registry and the guidelines will be inseparable.

Materialart: Online-Ressource

ISSN: 1744-9979 , 1744-9987

URL: Issue

URL: Article

DOI: 10.1111/tap.v25.6

DOI: 10.1111/1744-9987.13749

Sprache: Englisch

Verlag: Wiley

Publikationsdatum: 2021

ZDB Id: 2010864-3

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7

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Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes According to Baseline HbA1c and Insulin Use: An Analysis From the FIDELIO-DKD Study

Rossing, Peter ; Burgess, Ellen ; Agarwal, Rajiv ; [weitere]

American Diabetes Association ; 2022

In: Diabetes Care Vol. 45, No. 4 ( 2022-04-01), p. e888-e897

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In: Diabetes Care, American Diabetes Association, Vol. 45, No. 4 ( 2022-04-01), p. e888-e897

Kurzfassung: Finerenone significantly improved cardiorenal outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) in the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease trial. We explored whether baseline HbA1c level and insulin treatment influenced outcomes. RESEARCH DESIGN AND METHODS Patients with T2D, urine albumin-to-creatinine ratio (UACR) of 30–5,000 mg/g, estimated glomerular filtration rate (eGFR) of 25 to & lt;75 mL/min/1.73 m2, and treated with optimized renin–angiotensin system blockade were randomly assigned to receive finerenone or placebo. Efficacy outcomes included kidney (kidney failure, sustained decrease ≥40% in eGFR from baseline, or renal death) and cardiovascular (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure) composite endpoints. Patients were analyzed by baseline insulin use and by baseline HbA1c & lt;7.5% (58 mmol/mol) or ≥7.5%. RESULTS Of 5,674 patients, 3,637 (64.1%) received insulin at baseline. Overall, 5,663 patients were included in the analysis for HbA1c; 2,794 (49.3%) had baseline HbA1c & lt;7.5% (58 mmol/mol). Finerenone significantly reduced risk of the kidney composite outcome independent of baseline HbA1c level and insulin use (Pinteraction = 0.41 and 0.56, respectively). Cardiovascular composite outcome incidence was reduced with finerenone irrespective of baseline HbA1c level and insulin use (Pinteraction = 0.70 and 0.33, respectively). Although baseline HbA1c level did not affect kidney event risk, cardiovascular risk increased with higher HbA1c level. UACR reduction was consistent across subgroups. Adverse events were similar between groups regardless of baseline HbA1c level and insulin use; few finerenone-treated patients discontinued treatment because of hyperkalemia. CONCLUSIONS Finerenone reduces kidney and cardiovascular outcome risk in patients with CKD and T2D, and risks appear consistent irrespective of HbA1c levels or insulin use.

Materialart: Online-Ressource

ISSN: 0149-5992

URL: Article

DOI: 10.2337/dc21-1944

Sprache: Englisch

Verlag: American Diabetes Association

Publikationsdatum: 2022

ZDB Id: 1490520-6

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8

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Detection of Species of the Subgenus Leishmania Parasites Using Polymerase Chain Reaction and Southern Blotting

Uezato, Hiroshi ; Takei, Kimiko ; Maruno, Motoyoshi ; [weitere]

Wiley ; 2001

In: The Journal of Dermatology Vol. 28, No. 9 ( 2001-09), p. 475-480

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In: The Journal of Dermatology, Wiley, Vol. 28, No. 9 ( 2001-09), p. 475-480

Materialart: Online-Ressource

ISSN: 0385-2407

URL: Issue

URL: Article

DOI: 10.1111/jde.2001.28.issue-9

DOI: 10.1111/j.1346-8138.2001.tb00014.x

RVK:

XA 53120

Sprache: Englisch

Verlag: Wiley

Publikationsdatum: 2001

ZDB Id: 2222121-9

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9

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Early Phase Arterial Reaction Following Drug-Eluting and Bare-Metal Stent Implantation in Patients With ST-Segment Elevation Myocardial Infarction : Optical Coherence Tomography Assessment at 2 Weeks

Nishio, Ryo ; Shinke, Toshiro ; Morino, Yoshihiro ; [weitere]

International Heart Journal (Japanese Heart Journal) ; 2015

In: International Heart Journal Vol. 56, No. 4 ( 2015), p. 389-394

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In: International Heart Journal, International Heart Journal (Japanese Heart Journal), Vol. 56, No. 4 ( 2015), p. 389-394

Materialart: Online-Ressource

ISSN: 1349-2365 , 1349-3299

URL: Article

DOI: 10.1536/ihj.15-044

Sprache: Englisch

Verlag: International Heart Journal (Japanese Heart Journal)

Publikationsdatum: 2015

ZDB Id: 2202206-5

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10

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Abstracts—Dental radiology Vol. 37, 1997

Sasaki, Takehito ; Nishio, Masamichi ; Sano, Tsukasa ; [weitere]

Springer Science and Business Media LLC ; 1998

In: Oral Radiology Vol. 14, No. 1 ( 1998-6), p. 33-50

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In: Oral Radiology, Springer Science and Business Media LLC, Vol. 14, No. 1 ( 1998-6), p. 33-50

Materialart: Online-Ressource

ISSN: 0911-6028 , 1613-9674

URL: Article

DOI: 10.1007/BF02492610

Sprache: Englisch

Verlag: Springer Science and Business Media LLC

Publikationsdatum: 1998

ZDB Id: 2157096-6

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