GLORIA — GEOMAR Library Ocean Research Information Access

1

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Disability in Activities of Daily Living and Severity of Dyskinesias Determine the Handicap of Parkinson’s Disease Patients in Advanced Stage Selected to DBS

Coelho, Miguel ; Abreu, Daisy ; Correia-Guedes, Leonor ; [et al.]

IOS Press ; 2017

In: Journal of Parkinson's Disease Vol. 7, No. 2 ( 2017-05-16), p. 255-261

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In: Journal of Parkinson's Disease, IOS Press, Vol. 7, No. 2 ( 2017-05-16), p. 255-261

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-160848

Language: Unknown

Publisher: IOS Press

Publication Date: 2017

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2

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Cardiovascular Adverse Events Reported in Placebo Arm of Randomized Controlled Trials in Parkinson’s Disease

Alves, Mariana ; Caldeira, Daniel ; Rato, Miguel Leal ; [et al.]

IOS Press ; 2020

In: Journal of Parkinson's Disease Vol. 10, No. 2 ( 2020-04-03), p. 641-651

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In: Journal of Parkinson's Disease, IOS Press, Vol. 10, No. 2 ( 2020-04-03), p. 641-651

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-191907

Language: Unknown

Publisher: IOS Press

Publication Date: 2020

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3

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Quantitative Analysis Versus Visual Assessment of Neuromelanin MR Imaging for the Diagnosis of Parkinson’s disease

Reimão, Sofia ; Pita Lobo, Patrícia ; Neutel, Dulce ; [et al.]

IOS Press ; 2015

In: Journal of Parkinson's Disease Vol. 5, No. 3 ( 2015-09-14), p. 561-567

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In: Journal of Parkinson's Disease, IOS Press, Vol. 5, No. 3 ( 2015-09-14), p. 561-567

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-150551

Language: Unknown

Publisher: IOS Press

Publication Date: 2015

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4

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Gait Kinematic Parameters in Parkinson’s Disease: A Systematic Review

Bouça-Machado, Raquel ; Jalles, Constança ; Guerreiro, Daniela ; [et al.]

IOS Press ; 2020

In: Journal of Parkinson's Disease Vol. 10, No. 3 ( 2020-07-28), p. 843-853

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In: Journal of Parkinson's Disease, IOS Press, Vol. 10, No. 3 ( 2020-07-28), p. 843-853

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-201969

Language: Unknown

Publisher: IOS Press

Publication Date: 2020

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5

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Are Happiness and Well-being the Same Outcome?

Pona-Ferreira, Joana ; Ferreira, Joaquim J.

IOS Press ; 2020

In: Journal of Parkinson's Disease Vol. 10, No. 4 ( 2020-10-27), p. 1787-1788

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In: Journal of Parkinson's Disease, IOS Press, Vol. 10, No. 4 ( 2020-10-27), p. 1787-1788

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-202226

Language: Unknown

Publisher: IOS Press

Publication Date: 2020

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6

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Optimizing Treatment in Undertreated Late-Stage Parkinsonism: A Pragmatic Randomized Trial

Hommel, Adrianus L.A.J. ; Meinders, Marjan J. ; Weerkamp, Nico J. ; [et al.]

IOS Press ; 2020

In: Journal of Parkinson's Disease Vol. 10, No. 3 ( 2020-07-28), p. 1171-1184

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In: Journal of Parkinson's Disease, IOS Press, Vol. 10, No. 3 ( 2020-07-28), p. 1171-1184

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-202033

Language: Unknown

Publisher: IOS Press

Publication Date: 2020

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7

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Participatory Design in Parkinson's Research with Focus on the Symptomatic Domains to be Measured

Serrano, J. Artur ; Larsen, Frank ; Isaacs, Tom ; [et al.]

IOS Press ; 2015

In: Journal of Parkinson's Disease Vol. 5, No. 1 ( 2015), p. 187-196

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In: Journal of Parkinson's Disease, IOS Press, Vol. 5, No. 1 ( 2015), p. 187-196

Type of Medium: Online Resource

ISSN: 1877-718X , 1877-7171

URL: Article

DOI: 10.3233/JPD-140472

Language: Unknown

Publisher: IOS Press

Publication Date: 2015

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8

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Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson’s Disease

Domenighetti, Cloé ; Sugier, Pierre-Emmanuel ; Sreelatha, Ashwin Ashok Kumar ; [et al.]

IOS Press ; 2022

In: Journal of Parkinson's Disease Vol. 12, No. 1 ( 2022-01-21), p. 267-282

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In: Journal of Parkinson's Disease, IOS Press, Vol. 12, No. 1 ( 2022-01-21), p. 267-282

Abstract: Background: Previous studies showed that lifestyle behaviors (cigarette smoking, alcohol, coffee) are inversely associated with Parkinson’s disease (PD). The prodromal phase of PD raises the possibility that these associations may be explained by reverse causation. Objective: To examine associations of lifestyle behaviors with PD using two-sample Mendelian randomisation (MR) and the potential for survival and incidence-prevalence biases. Methods: We used summary statistics from publicly available studies to estimate the association of genetic polymorphisms with lifestyle behaviors, and from Courage-PD (7,369 cases, 7,018 controls; European ancestry) to estimate the association of these variants with PD. We used the inverse-variance weighted method to compute odds ratios (ORIVW) of PD and 95%confidence intervals (CI). Significance was determined using a Bonferroni-corrected significance threshold (p = 0.017). Results: We found a significant inverse association between smoking initiation and PD (ORIVW per 1-SD increase in the prevalence of ever smoking = 0.74, 95%CI = 0.60–0.93, p = 0.009) without significant directional pleiotropy. Associations in participants ≤67 years old and cases with disease duration ≤7 years were of a similar size. No significant associations were observed for alcohol and coffee drinking. In reverse MR, genetic liability toward PD was not associated with smoking or coffee drinking but was positively associated with alcohol drinking. Conclusion: Our findings are in favor of an inverse association between smoking and PD that is not explained by reverse causation, confounding, and survival or incidence-prevalence biases. Genetic liability toward PD was positively associated with alcohol drinking. Conclusions on the association of alcohol and coffee drinking with PD are hampered by insufficient statistical power.

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-212851

Language: Unknown

Publisher: IOS Press

Publication Date: 2022

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9

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Clinical Parameters and Tools for Home-Based Assessment of Parkinson’s Disease: Results from a Delphi study

Ferreira, Joaquim J. ; Santos, Ana T. ; Domingos, Josefa ; [et al.]

IOS Press ; 2015

In: Journal of Parkinson's Disease Vol. 5, No. 2 ( 2015-06-01), p. 281-290

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In: Journal of Parkinson's Disease, IOS Press, Vol. 5, No. 2 ( 2015-06-01), p. 281-290

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-140493

Language: Unknown

Publisher: IOS Press

Publication Date: 2015

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10

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The Parkinson’s Real-World Impact Assessment (PRISM) Study: A European Survey of the Burden of Parkinson’s Disease in Patients and their Carers

Tolosa, Eduardo ; Ebersbach, Georg ; Ferreira, Joaquim J. ; [et al.]

IOS Press ; 2021

In: Journal of Parkinson's Disease Vol. 11, No. 3 ( 2021-08-02), p. 1309-1323

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In: Journal of Parkinson's Disease, IOS Press, Vol. 11, No. 3 ( 2021-08-02), p. 1309-1323

Abstract: Background: A greater understanding of the everyday experiences of people with Parkinson’s disease (PD) and their carers may help improve clinical practice. Objective: The Parkinson’s Real-world Impact assesSMent (PRISM) study evaluated medication use, health-related quality of life (HRQoL) and the use of healthcare resources by people with PD and their carers. Methods: PRISM is an observational cross-sectional study, in which people with PD and their carers completed an online survey using structured questionnaires, including the Parkinson’s Disease Quality of Life Questionnaire (PDQ-39), Non-Motor Symptoms Questionnaire (NMSQuest) and Zarit Burden Interview (ZBI). Results: Data were collected from 861 people with PD (mean age, 65.0 years; mean disease duration, 7.7 years) and 256 carers from six European countries. People with PD reported a large number of different co-morbidities, non-motor symptoms (mean NMSQuest score, 12.8), and impaired HRQoL (median PDQ-39 summary score, 29.1). Forty-five percent of people with PD reported at least one impulse control behaviour. Treatment patterns varied considerably between different European countries. Levodopa was taken in the last 12 months by 85.9% of participants, and as monotherapy by 21.8%. Carers, who were mostly female (64.8%) and the partner/spouse of the person with PD (82.1%), reported mild to moderate burden (mean ZBI total score, 26.6). Conclusions: The PRISM study sheds light on the lives of people with PD and those who care for them, re-emphasising the many challenges they face in everyday life. The study also provides insights into the current treatment of PD in Europe.

Type of Medium: Online Resource

ISSN: 1877-7171 , 1877-718X

URL: Article

DOI: 10.3233/JPD-212611

Language: Unknown

Publisher: IOS Press

Publication Date: 2021

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