ISSN:
1437-2320
Keywords:
Cerebral blood flow
;
stroke
;
transient ischemic attack
;
xenon computerized tomography
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Several investigators have describedCT-negative low flow areas in TIA and stroke patients in the chronic phase. The emission tomographic SPECT image they employed has, in contrast to the xenon CT method, no direct relation to the x-ray transmission CT scan. The aim of our study was to study the phenomenon ofCT-negative low flow areas using the xenon CT method, a method especially well suited for such cases. 57 xenon CT examinations were performed in 40 TIA patients, and 56 xenon CT examinations in 32 stroke patients. Flow data from brain tissue which appeared to be anatomically intact in a slice 5 cm above the canthomeatal plane were analyzed. In the TIA group, the flow in the gray matter was found to be significantly lower on the clinically affected side: symptomatic side, 61.8 ± 14.7 ml/100 g/min; asymptomatic side, 66.4 ± 15.8 ml/100 g/min (p 〈 0.001). In the stroke group, the flow in the white matter was also affected; symptomatic side, 31.2 ± 9.8 ml/100 g/min; asymptomatic side, 35.3 ± 11.1 ml/100 g/min (p 〈 0.01). Gray matter: symptomatic side, 56.1 ± 11.4 ml/100 g/min; asymptomatic side, 66.0 ± 11.0 ml/100 g/min (p 〈 0.001). The findings indicate that the appearance ofCT-negative low flow areas in TIA and stroke patients during the chronic phase is the rule rather than the exception. Flow adaptation to anatomic changes not discernible by CT can be differentiated from clinically relevant flow impairment only by testing the cerebrovascular reserve.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01743986
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