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  • 1
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2018
    In:  American Journal of Gastroenterology Vol. 113, No. Supplement ( 2018-10), p. S1274-
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 113, No. Supplement ( 2018-10), p. S1274-
    Type of Medium: Online Resource
    ISSN: 0002-9270
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
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  • 2
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2018
    In:  American Journal of Gastroenterology Vol. 113, No. Supplement ( 2018-10), p. S1114-S1115
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 113, No. Supplement ( 2018-10), p. S1114-S1115
    Type of Medium: Online Resource
    ISSN: 0002-9270
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
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  • 3
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2018
    In:  American Journal of Gastroenterology Vol. 113, No. Supplement ( 2018-10), p. S1649-S1650
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 113, No. Supplement ( 2018-10), p. S1649-S1650
    Type of Medium: Online Resource
    ISSN: 0002-9270
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
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  • 4
    Online Resource
    Online Resource
    Global Cardiology Science and Practice ; 2020
    In:  Global Cardiology Science and Practice Vol. 2020, No. 3 ( 2020-12-30)
    In: Global Cardiology Science and Practice, Global Cardiology Science and Practice, Vol. 2020, No. 3 ( 2020-12-30)
    Abstract: Bilaterally absent superior vena cava (SVC) is extremely rare anomaly with a few case reports in the literature. Without associated congenital cardiac disease, these anomalies are asymptomatic. This report describes an adult patient with bilaterally absent SVC presenting with Mobitz type II heart block and a structurally normal heart.
    Type of Medium: Online Resource
    ISSN: 2305-7823
    Language: Unknown
    Publisher: Global Cardiology Science and Practice
    Publication Date: 2020
    detail.hit.zdb_id: 2738381-7
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  • 5
    In: Pharmacognosy Journal, EManuscript Technologies, Vol. 13, No. 2 ( 2020-03-04), p. 434-442
    Type of Medium: Online Resource
    ISSN: 0975-3575
    URL: Issue
    Language: Unknown
    Publisher: EManuscript Technologies
    Publication Date: 2020
    detail.hit.zdb_id: 2586850-0
    SSG: 15,3
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  • 6
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  American Journal of Gastroenterology Vol. 114, No. 1 ( 2019-10), p. S1384-S1385
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 114, No. 1 ( 2019-10), p. S1384-S1385
    Abstract: Burkitt's lymphoma is an aggressively growing tumor commonly, involving the jaw and facial bones. A rare variant of this type of lymphoma is found in immunocompromised patients specifically in the gastrointestinal tract, usually affecting the stomach, distal ileum, and cecum and rarely the duodenum. We are reporting a case of primary lymphoma of the duodenum in a patient with newly diagnosed AIDS. CASE DESCRIPTION/METHODS: A 50-years-old male with no significant past medical history presented with gradually progressive generalized weakness with easy fatigability of one-month duration. He had no history of shortness of breath, dysphagia, nausea, vomiting, hematemesis, melena, hematochezia or bleeding from any sites. Vitals were normal and examination was negative for abdominal tenderness, organomegaly or lymphadenopathy. Labs showed severe iron deficiency anemia with hemoglobin of 5.9 g/dl with ferritin of 21 ng/ml and Transferrin saturation of 8.8%. Other labs including WBC count, platelets count, creatinine, liver enzymes and LDH were normal. In suspicious of occult gastrointestinal tract bleeding, upper endoscopy was performed revealing a large semi circumferential malignant appearing mass partially obstructing the lumen of the third portion of the duodenum. Multiple biopsied where taken showing small bowel mucosa infiltrated by uniform, intermediate sized cells strongly staining positive for CD10, CD20, Ki-67 (100%) and BCL-6; diagnostic for Burkitt's lymphoma. CT Abdomen/Pelvis/Chest for evaluation of other masses or lymphadenopathy showed a 41 × 40 mm mass arising from the third and fourth portions of the duodenum with short segment wall thickening of the distal small bowel and soft tissue nodule in the right hemipelvis with no significant lymphadenoptahy. His labs reveleaed came positive for HIV-1 with 144,000 and CD4 count of 161. Bone marrow was negative for any involvement He received 2 cycles of alternating chemotherapy with R-CODOX-M and R-IVAC for 4 months duration. PET scan after 2 month of chemotherapy completion was negative for any uptake. Patient is currently doing well, on HAART therapy with no recurrence of his symptoms. DISCUSSION: Primary duodenal Burkitt lymphoma is a subtype of non-Hodgkin's lymphoma and represents an aggressive and rare malignancy with only a small number of cases reported worldwide. Clinical and radiological presentation is non-specific and usually mimics other gastric lymphomas, leading usually to late presentation and diagnosis.
    Type of Medium: Online Resource
    ISSN: 0002-9270 , 1572-0241
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
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  • 7
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  American Journal of Gastroenterology Vol. 114, No. 1 ( 2019-10), p. S965-S966
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 114, No. 1 ( 2019-10), p. S965-S966
    Abstract: Acquired benign Broncho-esophageal fistulas (BEF) are uncommon and develops as a complication of inflammatory processes, malignant neoplasm and traumas of the chest but it has been rarely reported with esophageal or tracheal stents. We are reporting a case of Lt BEF after 10 years of esophageal stent placement for recurrent benign esophageal stricture. CASE DESCRIPTION/METHODS: A 52 years-old-female with history of HIV-1 infection was admitted with dysphagia to solid food. Her condition started 10 years ago after she presented with progressive odynophagia and dysphagia to solids and liquids. EGD at that time showed giant aphthous esophageal ulcer, 25 to 34 cm from the incisors, involving entire esophageal circumference. Biopsy showed ulcerated squamous mucosa with diffuse acute and chronic inflammation, negative stains for acid fast bacilli, fungal infection, CMV and HSV. She was treated with pantoprazole, hydrocortisone and thalidomide without improvement of her symptoms. Repeated EGD showed formation of benign esophageal stricture with negative repeated biopsy results. Over 6 months, she underwent multiple balloon dilatation of the stricture until 16 to 20 mm × 120 mm in length, Polyflex stent was placed with improvement of her symptoms She was lost for follow up before presenting again with progressive dysphagia to solids of 3 months duration associated with progressive weight loss. Esophagogram showed stable position of the stent in the mid esophagus with stable dilated proximal esophagus and no esophageal stricture. Due to concern of stent malfunction, the stent was removed but the patient continued to have dysphagia. Repeated esophagogram four days later, showed contrast media in the Left main bronchus tracking to the left lower lung lobe. Bronchoscopy and upper endoscopy showed chronic acquired Broncho-esophageal fistula extending from the lateral edge of membranous left main bronchus to the esophagus, 25 cm from incisors. PEG tube was placed for nutrition and she is planned for fistula repair in two weeks. DISCUSSION: BEF is a serious condition and treatment is mandatory to avoid continuous aspiration, chronic sepsis, and pulmonary failure, mainly in immunocompromised patients. There are no studies on the incidence of such fistulas after esophageal stent placements. On the other hand, some studies favored tracheal or esophageal stents as a corrective measure, although neither are free from complications, and they are palliative measures, making surgical repair the best option.
    Type of Medium: Online Resource
    ISSN: 0002-9270 , 1572-0241
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
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  • 8
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  American Journal of Gastroenterology Vol. 114, No. 1 ( 2019-10), p. S1125-S1126
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 114, No. 1 ( 2019-10), p. S1125-S1126
    Abstract: Merkel Cell Carcinoma (MCC) is a rare and aggressive skin cancer that was first described in 1972. Lymph node metastases are common in MCC and distant metastases occur in 8.4% of cases. We present a case of MCC complicated by melena and obstructive jaundice from GI metastases. To the best of our knowledge, less than 20 cases were reported with a similar presentation. CASE DESCRIPTION/METHODS: The patient is a 67-year-old male with a history of CAD, COPD and metastatic MCC who was admitted with melena and severe blood loss anemia. He was diagnosed with MCC of the right eyebrow 2 years ago and had a recurrence in the parotid gland that was treated with resection, radiotherapy (RT) and chemotherapy. PET CT scan 3 months prior to admission showed no evidence of distant metastases. After resuscitation and initiation of appropriate medical therapy, the patient underwent an EGD that showed multiple (1 cm) lesions scattered in the stomach and a large (4 cm) ulcerated mass in the lesser curvature with stigmata of recent hemorrhage. Hemospray was applied successfully for hemostasis. Biopsies of the gastric lesions confirmed metastatic MCC. The patient was discharged home and was started on palliative immunotherapy (Atezolizumab) and RT. Repeated PET CT scan showed the progression of the disease with widespread lymphatic, pancreatic, right perinephric, diffuse gastric and bony metastases. Four weeks later he was admitted with jaundice. Bilirubin was 2.5 gm/dl, ALP 458, ALT 457 and AST 441. Abdominal ultrasound showed dilated intra and extrahepatic ducts. An ERCP was performed and it showed a distal CBD stricture. An uncovered metal stent was successfully placed. The patient continued to have recurrent melena and a repeated EGD showed a new friable 4 cm ulcerated periampullary duodenal mass that was not amenable to endoscopic intervention. Mesenteric arteriogram was performed and active bleeding from the duodenal mass with tumor blush in the third part of duodenum was seen. Coil embolization of the GDA and PDA was successfully performed with the cessation of the bleeding. The patient was discharged home to resume palliative RT and immunotherapy. DISCUSSION: Merkel cell carcinoma is rare and aggressive skin cancer. GI metastases are very uncommon. Close surveillance with PET CT scan is important and high suspicion of GI metastases should be exercised when clinically appropriate.
    Type of Medium: Online Resource
    ISSN: 0002-9270 , 1572-0241
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
    Location Call Number Limitation Availability
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  • 9
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  American Journal of Gastroenterology Vol. 114, No. 1 ( 2019-10), p. S1292-S1292
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 114, No. 1 ( 2019-10), p. S1292-S1292
    Abstract: Cystic echinococcosis (CE) is a complex, chronic and neglected disease with a worldwide distribution. The liver is the most frequent location of parasitic cysts. In humans, its clinical spectrum ranges from asymptomatic infection to severe, potentially fatal disease. We are presenting a case report of a patient with incidentally discovered liver hydatid disease after he was found to have suspicious liver cystic liver on renal ultrasound. CASE DESCRIPTION/METHODS: A 57-years-old male with history of hypertension and penile pain was referred to the Gastroenterology clinic after he was found to have a possible cystic liver lesion on renal ultrasound. He was originally from Palestine and moved to US 10 years ago. He did not have abdominal pain, icterus, nausea, vomiting or history of recent travel or liver disease. Examination was only relevant for non-tender, non-pulsatile, hepatomegaly with no palpable masses. Labs showed normal liver enzymes. CT Abdomen followed by MRCP showed 11.7 × 10.6 × 9.7 cm cystic mass within the right hepatic lobe, demonstrating multiple non enhancing daughter cysts within in, suggestive of hydatid disease. His serology was positive for Echinococcus granulosus antibodies. After discussion with the patient, he agreed for total cystectomy due to large size of the cyst. During the surgery, once the large cyst was mobilized, daughter cysts were first suctioned through a little puncture hole on the top of the cyst, until the large cavity was totally empty. During excision of the cyst wall, it was found to be tightly adherent to the liver tissue allowing only for excision of anterior cyst wall and omentoplasty. Pathology showed numerous scolexes consistent with Echinococcus Granulosus. He was given Albendazole 2 weeks prior the surgery and 4 weeks after with absence of recurrence on repeated imaging. DISCUSSION: Cystic echinococcosis is often asymptomatic and diagnosed accidentally during radiographic examination, surgery, or during evaluation of other clinical diagnoses. Potential presentations may be due to the mechanical effect of a large cyst on surrounding tissues, rupture of a cyst causing an acute hypersensitivity reaction, or complications such as biliary obstruction. Surgery has long been considered the best, if not the only, option in the treatment. However, in the past two decades, medical treatment, percutaneous procedures, and a “watch and wait” approach have been successfully introduced and have replaced surgery as the treatment of choice in selected cases.
    Type of Medium: Online Resource
    ISSN: 0002-9270 , 1572-0241
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
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  • 10
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  American Journal of Gastroenterology Vol. 114, No. 1 ( 2019-10), p. S508-S510
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 114, No. 1 ( 2019-10), p. S508-S510
    Abstract: EUS guided fine needle aspiration (FNA) of pancreatic cystic lesions (PCL) has become the standard diagnostic modality for pancreatic cysts. Current American Society of Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines recommended the use of periprocedural prophylactic antibiotics (PA), although data is equivocal. Our aim was to perform a systematic review and meta-analysis to evaluate the efficacy of PA in preventing cyst infection during EUS-guided aspiration of PCL and assess the rate of complications related to antibiotic use. METHODS: We included studies evaluating the outcomes of using PA in EUS-guided FNA of PCL. We searched PubMed, Embase, and Google Scholar through April 2019. Eligible studies were searched for variables of interest including infection of PCL and antibiotic-related complications. All statistical analyses were performed using the R Programming Language. Pooled rates of variables were reported as Relative risks (RR) with 95% confidence interval and heterogeneity was reported as I2 statistics. RESULTS: A total of 9 retrospective studies were eligible and included in the analysis. 6 studies compared the use of PA to no antibiotics while the other 3 did not have a comparison group. There were 1183 subjects in the antibiotic group and 579 subjects in the non-antibiotic group. Duration of antibiotics varied from a single intraprocedural dose to 3-5 days following the procedure. Multiple antibiotic regimens were used including ceftriaxone, quinolones, amoxicillin, and piperacillin/tazobactam. There was no statistically significant difference in the rate of cyst infection between patients receiving PA and those who did not (RR = 0.6, 0.21-1.75; I 2 = 0%) (Figure 1). 1.2% of patients receiving PA developed adverse events related to antibiotic use. In addition, there was no difference among subgroups when stratifying subjects by single dose and 3-5 days of antibiotics ( P = 0.619) (Figure 2). CONCLUSION: The incidence of infectious complications after EUS-guided FNA of PCL appears very low and the use of PA did not substantially reduce the risk. Antibiotic use is not free of adverse events. Further randomized controlled trials are needed to evaluate the appropriateness of current recommendations.
    Type of Medium: Online Resource
    ISSN: 0002-9270 , 1572-0241
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
    Location Call Number Limitation Availability
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