In:
Medicine & Science in Sports & Exercise, Ovid Technologies (Wolters Kluwer Health), Vol. 51, No. 1 ( 2019-1), p. 84-93
Kurzfassung:
Low-intensity endurance training (ET) performed with blood flow restriction (BFR) can improve muscle strength, cross-sectional area (CSA) and cardiorespiratory capacity. Whether muscle strength and CSA as well as cardiorespiratory capacity (i.e., V˙O 2max ) and underlying molecular processes regulating such respective muscle adaptations are comparable to resistance and ET is unknown. Purpose To determine the respective chronic (i.e., 8 wk) functional, morphological, and molecular responses of ET-BFR training compared with conventional, unrestricted resistance training (RT) and ET. Methods Thirty healthy young men were randomly assigned to one of three experimental groups: ET-BFR ( n = 10, 4 d·wk −1 , 30-min cycling at 40% of V˙O 2max ), RT ( n = 10, 4 d·wk −1 , 4 sets of 10 repetitions leg press at 70% of one repetition maximum with 60 s rest) or ET ( n = 10, 4 d·wk −1 , 30-min cycling at 70% of V˙O 2max ) for 8 wk. Measures of quadriceps CSA, leg press one repetition maximum, and V˙O 2max as well as muscle biopsies were obtained before and after intervention. Results Both RT and ET-BFR increased muscle strength and hypertrophy responses. ET-BFR also increased V˙O 2max , total cytochrome c oxidase subunit 4 isoform 1 abundance and vascular endothelial growth factor mRNA abundance despite the lower work load compared to ET. Conclusions Eight weeks of ET-BFR can increase muscle strength and induce similar muscle hypertrophy responses to RT while V˙O 2max responses also increased postintervention even with a significantly lower work load compared with ET. Our findings provide new insight to some of the molecular mechanisms mediating adaptation responses with ET-BFR and the potential for this training protocol to improve muscle and cardiorespiratory capacity.
Materialart:
Online-Ressource
ISSN:
1530-0315
,
0195-9131
DOI:
10.1249/MSS.0000000000001755
Sprache:
Englisch
Verlag:
Ovid Technologies (Wolters Kluwer Health)
Publikationsdatum:
2019
ZDB Id:
2031167-9
SSG:
31
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