ISSN:
1434-9949
Keywords:
Wegener's Granulomatosis
;
Necrotizing Scleritis
;
Polyarthritis
;
Focal Necrotizing Glomerulonephritis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A case report of a female patient with Wegener's granulomatosis is presented. After an initial involvement of the upper respiratory tract in the form of a sinusitis, there followed a severe necrotizing bilateral scleritis necessitating the enucleation of the left eye ball. Renal involvement developed as late as 24 months after the onset of the disease and led to renal failure within three months. Throughout the duration of her disease, the patient had joint symptoms in the form of episodes of migratory nondeforming polyarthritis. The administration of corticosteroids alone in daily doses up to 60 mg prednisone failed to control the progression of the disease, while immunosuppressive therapy with cyclophosphamide combined with methylprednisolone pulse therapy and haemodialysis resulted in a marked improvement of renal function and in the subsidence of the ocular and articular symptoms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02030979
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