ISSN:
1433-0350
Keywords:
Primitive neuroectodermal tumor
;
Extracranial metastases
;
Astròcytic differentiation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00308497
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