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  • 1
    Keywords: Abduction (Logic) ; Logic ; Logic ; Abduction (Logic) ; Abduction (Logic) ; Logic ; Abductie (logica) ; PHILOSOPHY ; Logic ; Electronic books ; Electronic books ; Abduktion ; Kognition ; Abduktion ; Kognition
    Description / Table of Contents: Acknowledgements. -- Preface. -- -- A Practical Logic of Cognitive Systems -- 1. Introduction -- 2. Practical Logic -- Conceptual Models of Abduction -- 3. The Structure of Abduction -- 4. Explanationist Abduction -- 5. Non-Plausibilistic Abduction -- 6. Diagnostic Abduction in AI -- 7. The Characteristic and the Plausible -- 8. Relevance and Analogy -- 9. Interpretation Abduction -- Formal Models of Abduction -- 10. A Glimpse of Formality -- 11. A General Theory of Logical Systems -- 12. A Base Logic -- 13. An Abductive Mechanism for the Base Logic -- Bibliography. -- Index
    Type of Medium: Online Resource
    Pages: Online-Ressource
    Edition: Elsevier e-book collection on ScienceDirect
    ISBN: 044451791X , 9780444517913
    Series Statement: A practical logic of cognitive systems v. 2
    RVK:
    Language: English
    Note: Includes bibliographical references (p. 443-472) and index , Acknowledgements. -- Preface. -- -- A Practical Logic of Cognitive Systems -- 1. Introduction -- 2. Practical Logic -- Conceptual Models of Abduction -- 3. The Structure of Abduction -- 4. Explanationist Abduction -- 5. Non-Plausibilistic Abduction -- 6. Diagnostic Abduction in AI -- 7. The Characteristic and the Plausible -- 8. Relevance and Analogy -- 9. Interpretation Abduction -- Formal Models of Abduction -- 10. A Glimpse of Formality -- 11. A General Theory of Logical Systems -- 12. A Base Logic -- 13. An Abductive Mechanism for the Base Logic -- Bibliography. -- Index. , The present work is a continuation of the authors' acclaimed multi-volume A Practical Logic of Cognitive Systems. After having investigated the notion of relevance in their previous volume, Gabbay and Woods now turn to abduction. In this highly original approach, abduction is construed as ignorance-preserving inference, in which conjecture plays a pivotal role. Abduction is a response to a cognitive target that cannot be hit on the basis of what the agent currently knows. The abducer selects a hypothesis which were it true would enable the reasoner to attain his target. He concludes from this fact that the hypothesis may be conjectured. In allowing conjecture to stand in for the knowledge he fails to have, the abducer reveals himself to be a satisficer, since an abductive solution is not a solution from knowledge. Key to the authors' analysis is the requirement that a conjectured proposition is not just what a reasoner might allow himself to assume, but a proposition he must defeasibly release as a premiss for further inferences in the domain of enquiry in which the original abduction problem has arisen. The coverage of the book is extensive, from the philosophy of science to computer science and AI, from diagnostics to the law, from historical explanation to linguistic interpretation. One of the volume's strongest contributions is its exploration of the abductive character of criminal trials, with special attention given to the standard of proof beyond a reasonable doubt. Underlying their analysis of abductive reasoning is the authors' conception of practical agency. In this approach, practical agency is dominantly a matter of the comparative modesty of an agent's cognitive agendas, together with comparatively scant resources available for their advancement. Seen in these ways, abduction has a significantly practical character, precisely because it is a form of inference that satisfices rather than maximizes its response to the agent's cognitive target. The Reach of Abduction will be necessary reading for researchers, graduate students and senior undergraduates in logic, computer science, AI, belief dynamics, argumentation theory, cognitive psychology and neuroscience, linguistics, forensic science, legal reasoning and related areas. Key features: - Reach of Abduction is fully integrated with a background logic of cognitive systems. - The most extensive coverage compared to competitive works. - Demonstrates not only that abduction is a form of ignorance p ...
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  • 2
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 14 (1980), S. 473-481 
    ISSN: 0091-7419
    Keywords: protein transport ; phosvitin ; receptor ; coated vesicles ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: By two independent methods, the solubilized receptor for phosvitin (PV) has a subunit MW of 116K. Affinity chromatography, showed that only 2 of the more than 25 proteins present in the total detergent solubilized oocyte membrane extract were retained on a PV-agarose column. These proteins of MW of 116K and 100K could be eluted from PV-agarose with free PV. By gel exclusion chromatography, the receptor-125I-PV complexes elute in the void volume of a Biogel A-1.5 column. When these void fractions were assayed by SDS-PAGE only a single protein of MW of 116K was observed in addition to 125I-PV.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 12 (1979), S. 491-504 
    ISSN: 0091-7419
    Keywords: oocyte protein transport ; receptor solubilization ; phosvitin receptor ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Phosvitin (PV), a subunit of a female-specific protein, vitellogenin, binds to oocyte membranes with a KD of 10-6 M. Binding reaches equilibrium within 30 min after incubation at 25°C. Bound 125I-PV dissociates from the membrane with a t1/2 of 13 h when incubated in buffer. However, when 125I-PV-labeled membranes are incubated in buffer containing 10-5 M unlabeled PV, 50% of the initially bound 125I-PV dissociates from the membrane within 10 min. These results support the conclusion that PV binds to a membrane-associated receptor.Solubilization studies show that Triton X-100 solubilizes up to 45% of the total membrane-bound 125I-PV. Gel-exculsion chromatography of the solubilized material yields a 500,000 dalton 125I-PV-containing complex separated from free 125I-PV. The 500,000 dalton complex completely dissociates to yield free 125I-PV when incubated with excess unlabeled PV. However, when incubated with (1) no addition, (2) IgG, or (3) serum albumin, the extent of dissociation is significantly reduced and is consistent with that which would be predicted on the basis of the observed dissociation rate in the absence of unlabeled PV.These results suggest that bound 125I-PV can only be displaced by unlabeled PV. These results also indicate that the 500,000 dalton species is a solubilized PV-receptor complex and that it is possible to solubilize the PV-receptor in an active form.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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