ISSN:
0749-1581
Schlagwort(e):
INADEQUATE
;
2D NMR
;
Carbon-carbon scalar coupling
;
Polarization transfer
;
Quaternary carbons
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The two-dimensional INEPT-INADEQUATE experiment gives correlation peaks for unprotonated carbons which show only half of the total available signal, because the enhanced 13C signal generated by polarization transfer is shared equally between protonated and unprotonated coupling partners by the double quantum filtration step. If precautions are taken to attenuate unwanted signals from protonated carbons, then the double quantum filtration step may be dispensed with, leaving a hydrogen-carbon-carbon relay sequence. This gives unidirectional coherence transfer, ensuring that the maximum possible signal is concentrated in a single cross-peak identifying the correlation between protonated and unprotonated carbons. By extending the basic HCC relay sequence to include an evolution period an enhanced 13C-13C COSY 2D spectrum may be produced, with the further advantage over the 2D INADEQUATE experiment that the range of 13C-13C coupling constants detectable is limited only by the available resolution.
Zusätzliches Material:
3 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/mrc.1260250217
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