ISSN:
1432-2013
Keywords:
Tubular compliance
;
Capillary diameter
;
Tubular diameter
;
Rat kidney
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Tubular compliance is the response of tubular diameter to changes in intratubular pressure [7]. Proximal tubular compliance was determined directly by measurements of tubular diameter and pressure and indirectly using a mathematical model of tubular fluid flow based on measurements of the hydraulic pressure gradients along the tubule under free flow conditions and during an induced pressure reduction at the end of the proximal tubule. The two independent methods yielded similar values for compliance. Proximal tubular complicance was found to depend upon the intratubular pressure: tubular compliance was significantly higher (P〈0.001) when the intratubular pressure was reduced below normal (1.0 μm cm H2O−1) than when the pressure was increased above the control value (0.4 μm cm H2O−1) Almost identical compliance values were measured in sodium pentobarbital and inactin anaesthetized rats (P〉0.8). Intratubular pressure changes resulted in inverse changes in the diameters of the adjacent capillaries, suggesting that the peritubular capillaries are distensible structures.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00584220
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