Publication Date:
2013-05-16
Description:
The EMBO Journal 32, 1365 (2013). doi:10.1038/emboj.2013.60 Authors: Si-Qiang Ren, Jing-Zhi Yan, Xiao-Yan Zhang, Yun-Fei Bu, Wei-Wei Pan, Wen Yao, Tian Tian & Wei Lu Direct phosphorylation of GluA1 by PKC controls α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor (AMPAR) incorporation into active synapses during long-term potentiation (LTP). Numerous signalling molecules that involved in AMPAR incorporation have been identified, but the specific PKC isoform(s) participating in GluA1 phosphorylation and the molecule triggering PKC
Keywords:
AMPA receptorsLTPp62PKCλPI3K
Print ISSN:
0261-4189
Electronic ISSN:
1460-2075
Topics:
Biology
,
Medicine
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